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differential acute algorithm pulmonary injury kidney management rheumatology anca antibody antineutrophil antinuclear basement classification disease diseases giomeruiar glomerulonephritis goodpastures kidneyinjury
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Differential Diagnosis ... dipstick, urine microscopy ... , ANA, Anti-GBM, ... Anti-ds-DNA, C3 ... #nephrology #causes
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
- Differential Diagnosis ... Glomerulonephritis • Anti-GBM ... antibodies • ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... - Differential Diagnosis ... Vasculitis • GN: ANCA ... , Anti-GBM, C3/C4 ... #nephrology #causes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Vasculitis: • Microscopic ... + 90% • Anti-GBM ... Jcortesizaguirr #ANA ... #diagnosis #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... Disease-specific testing: anti-ANCA ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
: (AKI, proteinuria ... EGPA) • Auto-antibodies ... Anti-GBM antibody ... usually low in anti-GBM ... Goodpasture's cause
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
hemorrhage Diagnosis ... : • Anti-GBM antibodies ... weeks By Tess Litchman ... #Goodpastures #AntiGBM ... #diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN) AKA ... dysmorphic RBC, RBC casts ... microangiopathy (TMA), anti-phospholipid ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
renal abnormalities ... often causes arthritis ... glomerulonephritis) • Anti-GBM ... LFT • ESR • ANA ... ) pattern: antibodies
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
mimicry or super-antigen ... levels • NMO-IgG (anti-AQP4 ... • Infectious causes ... AntiCRMP IgG, Anti-Hu ... Antiamphiphysin antibodies
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