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differential algorithm pulmonary renal acute antigbm basement classification disease giomeruiar goodpastures hematuria injury kidney kidneyinjury management membrane membranoproliferative mpgn proteinuria
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Rapidly Progressive Glomerulonephritis ... • Anti-GBM antibodies ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Glomerulonephritis ... - Differential Diagnosis ... Wegener's) • P-ANCA: Microscopic ... Churg Strauss) Anti-GBM ... #nephrology #causes
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... - Differential Diagnosis ... cells on urine microscopy ... wall) • Anti-GBM ... antibodies
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... dipstick, urine microscopy ... and signs • Glomerulonephritis ... Vasculits: ANCA, ANA, Anti-GBM ... #nephrology #causes
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... Differential Diagnosis ... polyangiitis, Microscopic ... ab, anti-GBM ab ... #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... proliferative • Anti-GBM ... antibodies ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... immune deposits on EM ... microangiopathy (TMA), anti-phospholipid ... #MPGN #nephrology ... #diagnosis #renal
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... EGPA) • Auto-antibodies ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
rapidly progressive glomerulonephritis ... hemorrhage Diagnosis ... : • Anti-GBM antibodies ... weeks By Tess Litchman ... #nephrology #pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... tract, and often causes ... ) • Anti-GBM - ... Dx: GPA, EGPA, microscopic ... C-ANCA) pattern: antibodies
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