12 results
diagnosis differential algorithm causes management pulmonary rheumatology neurology renal table treatment acute aki ana anca antibody antigbm antineutrophil antinuclear associations
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
selected glomerular diseases ... (IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... #nephrology #pathology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and their Disease ... - Graves' disease ... Microscopic polyangiitis ... Anti-GBM - Goodpasture's ... #rheumatology #antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Vasculitis: • Microscopic ... ANCA+ 90% • Anti-GBM ... disease - MPO>PR3 ... Antineutrophil #antibodies
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... testing: anti-ANCA ... ab, anti-GBM ab ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
proliferative • Anti-GBM ... antibodies ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
cells on urine microscopy ... disease • ... wall) • Anti-GBM ... antibodies ... • Pauci-immune disease
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... (Goodpasture's Disease ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... AntiGBM #diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Glomerulonephritis • Anti-GBM ... antibodies • ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
an autoimmune disease ... antibodies are ... - but 5% have anti—muscle-specific ... Hospital of Baltimore IM ... diagnosis #management #neurology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... EGPA) • Auto-antibodies ... ANCA antibody, Anti-GBM ... usually low in anti-GBM
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