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differential causes algorithm acute aki glomerulonephritis classification injury kidney pulmonary renal rheumatology vasculitis antigbm basement comparison disease diseases glomerular goodpastures
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... #diseases #nephrology ... comparison #table #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... ab, anti-GBM ab ... #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... post-infectious GN Anti-Glomerular ... + • c-ANCA: anti-proteinase ... #Differential #Diagnosis ... #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... cells on urine microscopy ... wall) • Anti-GBM ... with polyangiitis/microscopic ... #Differential #Diagnosis
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... hemorrhage Diagnosis ... : • Anti-GBM antibodies ... weeks By Tess Litchman ... #nephrology #pulmonary
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
- Differential Diagnosis ... Wegener's) • P-ANCA: Microscopic ... Churg Strauss) Anti-GBM ... #differential #diagnosis ... #nephrology #causes
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
- Differential Diagnosis ... • Vascular • Glomerular ... Immune-complex disease, Anti-GBM ... #Differential #Diagnosis ... #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... dipstick, urine microscopy ... Vasculits: ANCA, ANA, Anti-GBM ... , Anti-ds-DNA, C3 ... #nephrology #causes
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... immune deposits on EM ... microangiopathy (TMA), anti-phospholipid ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
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