21 results
diagnosis differential causes algorithm glomerulonephritis rheumatology acute aki pathology clinical diseases electronmicroscopy injury kidney membranous mgn pulmonary sem vasculitis anca
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
diseases Light Microscopy ... (IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... glomerular #diseases #nephrology
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Wegener's) • P-ANCA: Microscopic ... Churg Strauss) Anti-GBM ... differential #diagnosis #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Basement Membrane (GBM ... Linear, ribbon-like GBM ... IF • Majority anti-neutrophil ... + • c-ANCA: anti-proteinase ... Differential #Diagnosis #Nephrology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- SLE Anti-histone ... - SLE Anti-SSA ... (Ro), Anti-SSB ( ... Microscopic polyangiitis ... Celiac disease Anti-GBM
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
cells on urine microscopy ... nephropathy • Thin GBM ... wall) • Anti-GBM ... with polyangiitis/microscopic
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% ... Anti-Sm (Smith) ... Anti-histone (in ... Vasculitis: • Microscopic ... ANCA+ 90% • Anti-GBM
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Immune-complex disease, Anti-GBM ... Differential #Diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Vasculits: ANCA, ANA, Anti-GBM ... , Anti-ds-DNA, C3 ... Differential #Diagnosis #nephrology
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