12 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... Basement Membrane ... ab, anti-GBM ab ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Nephrotic syndrome ... Amyloid RPGN • Anti-GBM ... #nephrology #pathology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... #Goodpastures #AntiGBM ... #diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
of cases) 2 ... • Sjögren syndrome ... Vasculitis: • Microscopic ... ANCA+ 90% • Anti-GBM ... disease - MPO>PR3
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... life-threatening diseases ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... osmolarity If cause ... Vasculits: ANCA, ANA, Anti-GBM ... Differential #Diagnosis #nephrology ... #causes
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... • Hepatorenal syndromes ... Glomerulonephritis • Anti-GBM ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... = glomerular basement ... hemolytic-uremic syndrome ... Nephrocalcinosis causes ... #nephrology
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Viruses (HSV, EBV ... Miller-Fisher GBS ... ; Positive for anti-ganglioside ... Differential #Diagnosis #Causes ... #Neurology