10 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... (Pulmonary and renal ... ab, anti-GBM ab ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Framework PRE-Renal ... Shunting INTRA-Renal ... Immune-complex disease, Anti-GBM ... Drug-induced POST-Renal ... Differential #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Framework Pre-Renal ... Hypercalcemia, Renal ... Medications Intra-Renal ... Vasculitis • GN: ANCA, Anti-GBM ... Differential #Diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
urinary sediment, renal ... Vasculits: ANCA, ANA, Anti-GBM ... , Anti-ds-DNA, C3 ... HIV serology, renal ... Differential #Diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
at least 50% Renal ... Glomerulonephritis • Anti-GBM ... Sjögren) Post-Renal ... #KidneyInjury #Nephrology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Coxsackie, HIV, CMV, EBV ... Lyme myositis • Rhabdomyolysis ... /SSA, anti-La/SSB ... , anti-Sm, and anti-RNP ... Differential #Diagnosis #neurology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
immune deposits on EM ... microangiopathy (TMA), anti-phospholipid ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Rhabdomyolysis - Differential Diagnosis Framework
Rhabdomyolysis = Destruction of skeletal muscle with leakage of contents into circulation.
Rhabdomyolysis - ... Diagnosis Framework Rhabdomyolysis ... Coxsackie virus, EBV ... Amphetamines, LSD UW IM ... Diagnosis #Causes #nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Immunofluorescence Microscopy (IM ... Electron Microscopy (EM ... Amyloid RPGN • Anti-GBM ... glomerular #diseases #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... @PulmPEEPs #Anti ... AntiGBM #diagnosis #nephrology