24 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... ) DILI Types: ... Calculate R-Value ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Stepwise Diagnosis Algorithm ... DILI suspicion ... Injury #Diagnosis #Algorithm ... #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
abnormality vs bone Bili ... ALP ≥ 2x ULN R Value ... Transaminitis #diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... • Iatrogenic: DILI ... Unconjugated Bili ... differential #diagnosis #algorithm ... #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
LFTs) - Normal Values ... bilirubin (Conjugated/DBili ... LFTs #Laboratory #Values ... Interpretation #diagnosis #hepatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Differential Diagnosis Algorithm ... Prosthetic heart valves ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Janeway Lesions in Endocarditis seen on Physical Exam 

Dr Supradip Ghosh
@dr_supradip

36 year old male with history
sister shared these photos ... #Endocarditis #PhysicalExam ... #clinical #photo ... #dermatology #soles
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
rosea #clinical #dermatology ... #photo #PhysicalExam
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Unconjugated Bili ... > 90% of Total Bili ... #differential #Hepatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... biopsy • Lab values ... supporting hematologic