15 results
diagnosis hepatology hepatitis lfts transaminitis causes dili gastroenterology hepatocellular lactate management acidosis aflp aih alkaline alp autoimmune bilirubin chemistry classification
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Injury Hepatocellular ... Liver Injury ... • AST/ALT elevation ... Liver Injury? ... • R value = (ALT
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... ALT ≥ 3x ULN Cholestatic ... ALP ≥ 2x ULN R Value ... Hepatocellular injury ... injury Sinai
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... Acute Liver Injury ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... Bilirubin - +/- elevation ... Enzyme Elevation ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Thrombus, Vasospasm Cholestatic ... Hepatitis, TB Cholestatic ... #Injury #Differential ... #algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Calculate R-Value ... Mixed DILI • Cholestatic ... #differential # ... gastroenterology #algorithm ... gastroenterology #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm ... #hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Diagnosis Algorithm ... Definition: T.bili elevation ... = intrahepatic cholestasis ... MRCP, ERCP, liver ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... phosphatase) 2) Cholestatic ... Injury Differential ... #Injury #Differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... titres, ↑ IgG • Cholestatic ... dechallenge • Acute ... #Algorithm #hepatology
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