19 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Tests - Prolonged PT ... and Prolonged PT ... #Algorithm #Coagulation ... Abnormal #APTT #Laboratory ... #Hematology #Diagnosis
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged PT ... • Prolonged PT ... #INR #Differential ... Algorithm #Causes #Hematology ... #coagulation #disorders
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... platelet aggregation PT ... using INR use PT ... Scoring #diagnosis #hematology ... #laboratory
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... Fibrinogen: ↓ • PT ... treatment #management #hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
PT and/or aPTT) ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Hypophostphatemia Laboratory ... #Hemolysis #Differential ... #Diagnosis #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... #Coagulation #Cascade ... thrombin #clot #PT ... diagnosis #models #hematology ... #pathophysiology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Congenital intrinsic coagulation ... intravascular coagulation ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... for a Prolonged PT ... and aPTT If the PT ... Causes #diagnosis #differential ... #hematology #coagulation
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
LFTs) - Normal Values ... Prothrombin Time (PT ... #Tests #LFTs #Laboratory ... #Values #Interpretation ... #diagnosis #hepatology