12 results
diagnosis liver transaminitis algorithm hepatocellular management arterial biliary causes chemistry cholangitis cholestatic cirrhosis dili drug elevation embolism enzymes fatty function
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs ... ≥ 2x ULN R Value ... Hepatocellular injury ... #FunctionTest #LFTs ... Transaminitis #diagnosis #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... ) - Differential ... Drug-induced liver injury ... #Differential # ... Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... , Toxic Hepatitis ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... • Pregnancy - AFLP ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential ... • Infections: Hepatitis ... Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
dose dependent injury ... Chronic - ongoing ↑ LFTs ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... #hepatitis #differential ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Liver #Pregnancy #hepatology
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