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diagnosis hepatology management lfts algorithm causes workup hepatitis rheumatology syndrome aih alkaline alp autoimmune chemistry classification disorders elevation enzymes gastroenterology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Defects, Drugs, Liver ... Hypophostphatemia Laboratory ... #Diagnosis #hematology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... LFTs) - Normal Values ... #Tests #LFTs #Laboratory ... #Values #Interpretation ... #diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... of liver disease ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... • R value = (ALT ... Transaminitis #diagnosis #differential ... #hepatology
Lab patterns seen in Inborn Errors of Metabolism A table of lab values compiled from UpToDate and
A table of lab values ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... Genetics #IEM #Laboratory
Approach to a Positive (+) Rheumatoid Factor (RF) (+) RF does not always = RA Rheumatic disorders: •
Inflammatory disorders of Liver ... Rheumatoid #Factor #RF #rheumatology ... #laboratory #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... In liver, 80% of ... Chemistry #Tests #Laboratory ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... Most common symptoms ... disease - Bone symptoms
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... duplex or CTA • Liver ... Liver biopsy • ... biopsy • Lab values ... supporting hematologic
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