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diagnosis causes differential secondary nephrology hypokalemia potassium workup low altered ams cardiology cosyntropin cushing early encephalopathy evaluation hormone hypercortisolism hyperfunction
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... of hypokalemia starts ... the existence of hypertension ... , Congenital adrenal ... hyperplasia • Cushing's
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm Primary (Essential) (95%) - Onset between age
Differential Diagnosis Algorithm ... Glucocorticoid excess (Cushing ... syndrome or disease ... #HTN #Cardiology ... Differential #Diagnosis #Algorithm
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Carbenoxolone, SAME, Cushing ... Syndrome • HTN ... secreting tumor, Primary ... Differential #Diagnosis #Algorithm
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
Endocrinopathies: • Cushing ... ’s syndrome • ... Primary aldosteronism ... with compensatory HTN ... • Serotonin syndrome
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Cushing Syndrome ... Testing Algorithm ... weakness, refractory hypertension ... Hormone • MRI of adrenal ... #algorithm #endocrinology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
Differential Diagnosis Algorithm ... Consider secondary HTN ... multi-drug resistance) Renal ... • Steroids (Cushing's ... #HTN #Secondary
Adrenal Incidentalomas: Hormone Evaluation • Zona Glomerulosa: Primary Hyperaldosteronism? - Aldosterone and renin
Zona Glomerulosa: Primary ... hypokalemia and/or hypertension ... Zona Fasciculata: Cushing ... Syndrome? ... Diagnosis #workup #endocrinology
Secondary causes of Hypertension • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Secondary causes of Hypertension ... Renal Disease ... Renovascular • Primary ... Other low renin HTN ... causes: Cushing's
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Differential Diagnosis Algorithm ... Hypertensive: ... High Al, Low R - Primary ... , Congenital Adrenal ... Al, Normal R - Cushing's
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis Algorithm ... Deprivation • Primary ... Endrocrine • Cushing's ... • Congenital Adrenal ... #endocrinology
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