28 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... only curative treatment ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... PLEX and RTX • Short-term ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... Management • ... #Diagnosis #Management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
priapism • Lab values ... organ damage • Treatment ... sudden death • Lab values ... #TLS #diagnosis ... #management #hematology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... Decompensated CHF ... Abdominal compartment syndrome ... #criticalcare # ... #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... sepsis), PE, DAH, CHF ... Renal Failure Treatment ... #management #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... and Management ... Treatment: • Global ... Gastroenterology and Hepatology ... #Diagnosis #Management
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... Excellent response to treatment ... Abnormal laboratory values ... #Hematology #Dermatology