15 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... Proteinuria often ... diabetes)) #Glomerular ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... the patient have glomerular ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... • Evidence of glomerular ... bleeding (proteinuria ... Diagnosis #Algorithm #Workup ... #urine
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
(Negative urine ... • Fanconi's syndrome ... • Drugs Glomerular ... ) - Active urine ... #Nephrology #Differential
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Rapidly Progressive Glomerulonephritis ... function over a short ... disease (hematuria, proteinuria ... staining #Glomerulonephritis ... Differential #Diagnosis #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
membrane; GN = glomerulonephritis ... hemolytic-uremic syndrome ... arbitrarily defined as urine ... because nephritic urine ... #syndrome #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
disease 24-hour urine ... Spot PC (protein ... Serum or urine for ... #testing #workup ... #diagnosis #glomerulonephritis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... formation along glomerular ... anti-phospholipid syndrome ... #MPGN #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... and signs • Glomerulonephritis ... Abdominal compartment syndrome ... • Cardio-renal syndrome ... #Injury #AKI #Workup
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... - Proteinuria ... • Nutcracker syndrome ... #nephrology #renal