28 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... of liver disease ... Calculate R-Value ... gastroenterology #algorithm ... gastroenterology #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Cholestasis - Drugs ... - Bone symptoms ... #Algorithm #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... HELLP - Grafts, Valves ... , Liver Disease, ... Laboratory Tests ... #hematology
Causes of Tremors - Movement Disorders - Differential Diagnosis Algorithm
Action Tremor - Occurs During Voluntary Muscle
- Differential Diagnosis ... Algorithm Action ... Tremor - Occurs at Rest ... MovementDisorders #Neurology ... #Algorithm #Causes
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Drugs 5. ... and duration of symptoms ... angioedema Other symptoms ... fatigue, Nausea, abdominal ... Cold #Urticaria #diagnosis
Diagnostic Algorithm for Dizziness and Vertigo
Peripheral Vertigo:
 • Attacks: Sudden, severe, can last anywhere from seconds
Diagnostic Algorithm ... No auditory symptoms ... Méniére's disease ... Long symptom-free ... #differential #diagnosis
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... Tropheryma whipplei Symptoms ... Abdominal pain; ... positive T. whipplei test ... #diagnosis #algorithm
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... >1.5, and both values ... suspect drug within ... atypical laboratory tests ... Hepatitis #AH #hepatology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
• Inflammatory disease ... Urethral stricture/valves ... /phimosis #Diagnosis ... #Differential #Nephrology ... GrepMed Recommended Text
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... >1.5, and both values ... suspect drug within ... atypical laboratory tests ... #Hepatology #AIH