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Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Calculate R-Value ... #DILI #Drug #induced ... gastroenterology #hepatology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and initial management ... HIT laboratory tests ... #Diagnosis #Management ... #Hematology #HIT ... #Heparin #Induced
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... : • Clinical Suspicion ... approach for post-test ... : Confirmatory test ... #Hematology #HemeOnc
Cerebral Toxoplasmosis 
- Most comrnon CNS infection in patients with AIDS 
who are not receiving appropriate
prophylaxis Clinical ... • Seizure Management ... pyrimethamine-induced ... hematologic toxicity ... Toxoplasmosis #Diagnosis
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... >1.5, and both values ... Possible drug-induced ... atypical laboratory tests ... Hepatitis #AH #hepatology
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Pathogenesis and Clinical ... PCL: The PCL is injured ... & Valgus Stress ... & Valgus Stress ... classification #diagnosis
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... >1.5, and both values ... Possible drug-induced ... atypical laboratory tests ... #Hepatology #AIH
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
Behcet's Syndrome - Diagnosis ... Diagnostic Criteria ... Abnormal pathergy test ... Most Common Clinical ... #criteria #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ulceration • Ocular ... Behcet syndrome (Clinical ... #management #signs ... #symptoms #rheumatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Test for the respective ... node biopsy • Clinical ... biopsy • Lab values ... supporting hematologic ... UnknownOrigin #workup #diagnosis