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hematology management differential cardiology hypercoagulable oncology antiphospholipid apls apml cancer causes chestpain chronic cll criteria dermatology dermatosis differentiation fever fuo
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
history of prior venous ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... smear • Signs of VTE ... Venous duplex or ... biopsy • Lab values ... #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... : - If febrile ... #TLS #diagnosis ... #management #hematology
Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
GPA, IgA, MPA) Acute ... - Venous (least ... Antiphospholipid syndrome ... hypovolemia), Meds/Treatments ... #algorithm
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... febrile neutrophilic ... Renal Failure Treatment ... #management #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... (Acute Febrile ... Excellent response to treatment ... Abnormal laboratory values ... #Acute #Febrile
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... or subacute febrile ... • Bicytopenia Treatment ... #hematology
Right-Sided Heart Failure - Differential Diagnosis Algorithm Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
Algorithm Cardiac ... Cardiomyopathy - Valves ... Disease • Acute ... Respiratory Distress Syndrome ... • Pulmonary Veno-Occlusive
HEART Score – A Tool For the ED The HEART score is an excellent tool that
with possible Acute ... Coronary Syndrome ... admission for further workup ... and treatment versus ... heart-score-major-cardiac-events #Diagnosis
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