9 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... • R value = (ALT ... #Cholestatic #Transaminitis ... #differential #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... ALP ≥ 2x ULN R Value ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... duplex or CTA • Liver ... Liver biopsy • ... biopsy • Lab values ... supporting hematologic
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... or symptoms of liver ... Calculate R-Value ... differential #Diagnosis #Management ... gastroenterology #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Interpretation of LFTs R-value ... Identify Acute Liver ... #differential #Hepatology ... #transaminitis
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
Non-alcoholic fatty liver ... with NAFLD or liver ... fibrosis score with values ... algorithm #Referral #Management ... #Hepatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
or sed rate): Value ... GCA, but normal values ... thrombocytosis, transaminitis ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Artificial Liver Support Systems
Bridge between transplantation to allow a patient's liver to recover
When used: Acute liver
Artificial Liver ... allow a patient's liver ... Hemodiafiltration - Works ... Support #Systems #hepatology ... #management