28 results
diagnosis differential causes hemolytic workup management atlas chronic extravascular intravascular leukemia lymphocytic morphology thrombocytosis agglutinin aplastic blood bloodcell bodies calculation
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Anemias (AIHAs) ... Anemias (AHAs) ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Anemias (MAHA) ... #Normocytic #Anemia ... #Causes #Hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... breakdown • Anaemia ... #Hemolytic #Anemia ... #Algorithm #Differential ... Causes #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... anemia • Hypochromic ... & microcytic RBCs ... anemia (TTP, HUS ... #Anemia #Differential
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Sideroblastic anemia ... anemia Stomatocyte ... liver disease, Malignant ... differential #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology ... spherocytosis, Hemolytic ... Stomatocytes - Malignant ... Schistocytes - Hemolytic ... #differential #hematology
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
anemia • Heinz ... Sideroblastic anemia ... , Hemolytic anemia ... Thalassemia, Sickle cell ... Bodies #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) (e.g. lupus, CLL ... • Intrinsic RBC ... differential #diagnosis #hematology ... #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... valve, vasculitis, malignant ... #Anemia #Differential ... #workup #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
organ or stem cell ... Trousseau's • Malignant ... anemia" • HELLP ... differential #diagnosis #hematology ... #hemolysis
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