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differential neurology syndrome erythematosus classification disease summary systemic vasculitis druginduced nephritis thrombocytopenia activation als amyotrophic approach arthritis behcet bruising capillary
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology # ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... life-threatening • Treatment ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... #Nephritis #SLE ... Classification #Classes ... #differential #diagnosis ... #management #nephrology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology # ... management
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
many differential diagnoses ... including in children (pediatric ... SLE) 10) When ... #diagnosis #sle ... erythematosus #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... #treatment #management ... #rheumatology # ... nephrology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... #management #treatment ... #summary #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Vascular Sludging ... (e.g. systemic lupus ... classification #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
and Management ... , Cough • +/-Nausea ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi ... #management #treatment
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