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diagnosis hematology differential algorithm management cardiology dyspnea table thrombocytopenia aflp chronic classification hellp leukemia mds monoclonal myelodysplastic obstetrics palpitations pathophysiology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Tamponade Pulmonary ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia • ... #pulmonary
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... Management #treatment #hematology ... #oncology
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Causes of Chronic ... Cardiomyopathy Valvular ... Acute Coronary Syndrome ... - Other • Anemia ... Diagnosis #Algorithm #Causes
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Myelodysplastic syndrome ... PD deficiency, Pulmonary ... Hemolytic uremic syndrome ... #differential #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Causes of Pleural ... Malignancy • Pulmonary ... embolism • Collagen vascular ... • Asbestos • Uremia ... Pleural #Effusion #Pulmonary
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Causes of Dyspnea ... Cardiomyopathy • Valvular ... Superior vena cava syndrome ... • Anxiety • Anemia ... Diagnosis #Algorithm #Causes
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
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