125 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
, vascular disorders ... : - Thrombocytopenia ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Diagnosis Algorithm Thrombocytopenia ... Sequestration Disordered ... Vascular System ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... PT, aPTT(liver disease ... (CVID, WAS), (neurologic ... bypass), LFT (liver disease ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... • Rheumatic disorders ... • Celiac disease ... following EtOH induced thrombocytopenia ... #Hematology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... or peripheral neurologic ... disease • Myasthenia ... gravis • Muscular ... #neurology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... differential #diagnosis #hematology
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Mucous Membrane Disorder ... Blisters - Primary Dermatologic ... Stevens-Johnson Syndrome ... • Behcet's syndrome ... Diagnosis #Algorithm #causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Non-lmmune: • HELLP Syndrome ... Heart Valve) #Thrombocytopenia ... Diagnosis #Algorithm #Causes ... #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... inherited bleeding disorder ... platelet count (mild thrombocytopenia ... VonWillebrand #Disease ... #Diagnosis #Hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
and less common diseases ... Inflammatory causes ... polychondritis • Behcet disease ... optica spectrum disorder ... #neurology #inflammatory