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diagnosis differential management algorithm sle disease erythematosus msk signs symptoms syndrome systemic vasculitis classification joint pain treatment workup druginduced hepatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... (RA), Systemic lupus ... (SPA) • Other Causes ... Mycobacterial Causes ... Differential #Diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... • Arthritis domain ... least 2 joints • Neurologic ... pericarditis • Hematologic ... Erythematosus #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... Myopathy (Also caused ... #Systemic #Lupus ... Complications #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... • Rheumatoid Arthritis ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... Diagnosis #Algorithm #Causes ... #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... Erythematosus #Diagnosis #Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... diagnosis #algorithm #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... rare with ~100 cases ... : vacuolar myopathy ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
invade URT & via hematologic ... altered LOC; septic arthritis ... endotoxin induces vascular ... CNS and hematologic ... peds #pediatrics #pathophysiology
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