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diagnosis management differential hematology syndrome algorithm neurology dermatology signs symptoms radiology workup msk oncology pathophysiology pharmacology pocus vasculitis arthritis erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Inflammatory • Systemic Lupus ... Spherocytosis • Acquired causes ... Diagnosis #Algorithm #Causes ... #Hematology
Hemoptysis - Differential Diagnosis Framework Airways: • Bronchitis • Bronchiectasis • Malignancy: Primary bronchogenic CA, Endobronchial
Goodpastures, Lupus ... Cocaine Cardiac/Vascular ... Osler-Weber-Rendu syndrome • Valvular ... Disease • Left ... Diagnosis #pulmonary #causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... Benefits: ↓ Disease ... Worsening of other diseases ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
platelet disorders, vascular ... Etiology: • Vascular ... Disruptions in vascular ... - Bone marrow disease ... #rheumatology #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Vascular System ... TeIangiectasia Vascular ... Diagnosis #Algorithm #Causes ... #Hematology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... with more severe disease ... Treatment: • ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... immunosuppressive meds) Vascular ... #Syndrome #Treatment ... #pharmacology #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... Evolution: Chronic disease ... comparison #table #rheumatology
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