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hematology causes workup management chronic classification oncology aki blood hemolysis pulmonary renal systemic treatment abnormal acute atlas cll dermatology disorders
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm ... • Extrinsic RBC ... • Intrinsic RBC ... #Anemias #Differential ... #Diagnosis #Algorithm
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Diagnosis Algorithm ... Decreased WBCs ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... Diagnosis #Algorithm
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Decreased RBC ... Disease • Marrow ... Disorder • RBC ... #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Diagnosis Algorithm ... hypertension • Unusual RBC ... #Anemia #Differential ... #Diagnosis #Algorithm
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... ↑ LDH • Anti-RBC ... • Blood smear: Differential ... #Anemia #diagnosis ... management #treatment #rheumatology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Diagnosis Algorithm ... sediment - WBC/ ... RBC casts ... Minimal change disease ... Diagnosis #Algorithm
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... , Hemolytic anemia ... : Hemoglobin H disease ... Sickle cell, MDS #RBC ... Inclusions #Bodies #diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Spherocytosis, G6PD, PK, HbC ... Non-megaloblastic: Liver disease ... Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
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