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RBC Casts on Urine Microscopy

Dr. Telma Lemos @TELMALEMOS10

#RBC #Casts #Urine #Microscopy #clinical #nephrology
RBC Casts on Urine ... Microscopy Dr. ... #Casts #Urine # ... Microscopy #clinical ... #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... • RBC Casts - ... glomerulonephritis • WBC ... #Urine #Microscopy ... #nephrology #interpretation
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... also be seen if urine ... fresh at time of microscopy ... #Microscopy #Atlas ... key #diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria (Negative urine ... sediment - WBC/ ... RBC casts ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Glitter Cells on Urine Microscopy
Glitter cells in the urine are viable and pale staining WBCs with
Microscopy Glitter ... cells in the urine ... pale staining WBCs ... #Microscopy #clinical ... #nephrology
Trichomonas on Urine Microscopy

Trichomonas organisms adjacent to mixed cellular cast containing WBC's, tubular epithelial cells, and
Trichomonas on Urine ... Microscopy Trichomonas ... mixed cellular cast ... RBC - brightfield ... #Trichomonas #Urine
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
unilateral flank pain ... WBCs, or urine ... casts, dysmorphic ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology
Urine Microscopy Instructions
1) Spin fresh urine sample (10-15mL) in a centrifuge for 3-5 minutes - Don't
Urine Microscopy ... 1) Spin fresh urine ... sample (10-15mL) in ... under lower power (casts ... #nephrology #diagnosis
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sterile pyuria, WBC ... casts, eosinophiluria ... , microscopic hematuria ... proteinuria, granular casts ... #Algorithm #nephrology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
e.g AEIOU ) or anuria ... IMPROVEMENT If the urine ... Assess UA w/ microscopy ... for WBCs, RBCs, ... casts, crystals