55 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Anemias (AIHAs) ... Anemias (AHAs) ... • Extrinsic RBC ... • Intrinsic RBC
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... Extravascular Hemolysis ... Haptoglobin Urine ... hemosiderin Urine ... #Anemia #Laboratory
Urine Microscopy and Casts - Image Atlas Key

- Squamous Epithelial Casts
- Transitional Epithelial Cells
- Renal Tubular
Urine Microscopy ... Hyaline Cast - WBCs ... Granular Casts - WBC ... JoseTesser) #Urine ... #Microscopy #Casts
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased WBCs ... Normal/lncreased WBCs ... Bleed • Hemolysis ... Microangiopathic Hemolytic
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Microangiopathic Hemolytic ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic ... diagnosis #hematology #microscopy
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... AIHA • Anemia ... ↑ LDH • Anti-RBC ... #Anemia #diagnosis
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology of Hemolytic ... Anemia - Defects ... in RBC internal ... Pathophysiology #Hemolytic ... #Anemia #hematology
RBC Casts on Urine Microscopy

Dr. Telma Lemos @TELMALEMOS10

#RBC #Casts #Urine #Microscopy #clinical #nephrology
RBC Casts on Urine ... Microscopy Dr. ... TELMALEMOS10 #RBC ... #Casts #Urine # ... Microscopy #clinical
Diagnostic Criteria for Scleroderma Renal Crisis 

1. New onset blood pressure >150/85 mm Hg OR increase
Microangiopathic hemolytic ... anemia - Findings ... hematuria on urine ... blood cells on urine ... microscopy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... anemia): ... • Intrinsic RBC ... diagnosis #hematology #anemia