28 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
: B-symptoms, bruising ... hepatomegaly • Labs: anemia ... Matthew Ho, MD ... Diagnosis #Algorithm #hematology ... #WBC #Leukemoid
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... • ↓ WBC • ↓ ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #MDS #Diagnosis ... #hematology #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... if neutropenic fever ... Can progress to MDS ... #diagnosis #management ... #treatment #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5. ... Drugs Nutritional ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5 ... Drugs Nutritional ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
fevers, night ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... - 80% have fever ... • Lab values: WBC ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... experience some symptoms ... RBC are produced ... Pancytopenia is a hematologic ... Satyendra Dhar MD