38 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Treatment: ... #oncology #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... ↑ LDH • Anti-RBC ... Autoimmune #Hemolytic #Anemia ... diagnosis #management #treatment
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... HEMATOLOGIC ONCOLOGIC ... of breath • Neurologic ... Leukostasis: • WBC ... STRUCTURAL ONCOLOGIC
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... transformation) Treatment ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology
Dyspnea - Considerations with Malignancy
Directly Malignancy Related:
 - Lymphangitic spread to lung
 - Malignant pleural effusion
metastases Treatment ... - Cytopenias (anemia ... differential #diagnosis #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... effect following treatment ... Iron deficiency anemia
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... if high risk if WBC ... Renal Failure Treatment ... QD until normal WBC ... management #hematology #oncology
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
Algorithm for the Treatment ... Nonpharmacologic Treatments ... Pharmacologic Treatments ... Uremic #Pruritus #uremia ... #management #nephrology
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
• Anterograde amnesia ... Encephalopathy Treatment ... Korsakoff #Syndrome #neurology