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differential algorithm anemia management causes oncology workup treatment classification autoimmune hemolysis liver microscopy monoclonal rbc reactions syndrome transfusion atlas comparison
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... • Extrinsic RBC ... • Intrinsic RBC ... #Differential #Diagnosis ... #Algorithm #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... cold agglutin disease ... • Intrinsic RBC ... #differential #diagnosis ... #hematology #anemia
Interpretation of Components of the CBC (Complete Blood Count) #CBC #Interpretation #CompleteBloodCount #Hematology #Differential #Diagnosis #Laboratory
Components of the CBC ... (Complete Blood ... Count) #CBC ... CompleteBloodCount #Hematology ... #Differential #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased WBCs ... Normal/lncreased WBCs ... Bleed • Hemolysis ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , McLeod blood group ... Microangiopathic Hemolytic ... #differential #diagnosis ... #hematology #microscopy
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Asplenism, Severe hemolytic ... Sideroblastic anemia, Hemolytic ... : Hemoglobin H disease ... Inclusions #Bodies #diagnosis ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... #Anemia #diagnosis ... management #treatment #rheumatology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... cells: Sickle cell disease ... Smear #Analysis #hematology ... interpretation #clinical
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... ARUPConsult @ARUPLabs #Hemolytic ... #Differential #Diagnosis ... Algorithm #workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... , Drugs, Liver Disease ... - Peripheral Blood ... #hematology
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