WBC blood treatment hematology disease syndrome infectiousdiseases rheumatology workup management systemic autoimmune testing

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52 results

Warm Antibody Autoimmune Hemolytic Anemia
1) DIAGNOSE AIHA
• Anemia: macrocytic > normocytic, ↑ reticulocytes
•

↑ LDH • Anti-RBC ... type ± C3d • Blood ... FOR a cause → Systematic ... Anemia #diagnosis #management ... #treatment #rheumatology

Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3

autoimmune disease ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... signs #symptoms #testing ... #workup

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup ... Autoimmune Mediated ... Eating disorders ... Metastatic Disease ... Diagnosis #Algorithm #Hematology

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

→ Refer to hematology ... for workup, including ... : Acute blood loss ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

hypertension • Unusual RBC ... acanthocytes - Consider RBC ... elliptocytosis, autoimmune ... Diagnosis #Algorithm #workup ... #hematology #testing

$Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:$

Behcet's Syndrome ... : • Treatment: ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology

Hemolysis - Differential Diagnosis Framework

1) Environment
- Fragmentation
- MAHA: TTP, HUS, DIC, HELLP

Membrane): - Autoimmune ... Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... - Peripheral Blood ... Differential #Diagnosis #hematology

Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
• Associated

block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: • ... Summary #diagnosis #rheumatology ... #management

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

Diagnosis and Workup ... plateletcount), peripheral blood ... smear, HIV/HCV testing ... PT, aPTT(liver disease ... #hematology

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