23 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... Juvenile Idiopathic Arthritis ... lupus erythematosus ... lupus erythematosus ... #Antibodies #ANA
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
arthritis (RA) ... or systemic lupus ... SLE) Signs / Symptoms ... #Syndrome #Pathophysiology ... #Diagnosis #Signs
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Juvenile Idiopathic Arthritis ... scleroderma), Rheumatoid Arthritis ... , Sjögren Syndrome ... Juvenile Idiopathic Arthritis
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
large vessels - Arteritis ... temporalis (giant-cell arteritis ... - Takayasu arteritis ... lupus erythematosus ... #Rheumatology #
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
: Giant Cell Arteritis ... GCA), Takayasu's arteritis ... , Cogan's Syndrome ... RD), Rheumatoid Arthritis ... lupus erythematosus
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... #erythematosus # ... signs #symptoms ... #diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... • Sjögren syndrome ... #antibodies #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... arthritis, adult-onset ... Arthritis: • ... to: Arthritis, ... #Diagnosis #Rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Inflammatory causes ... • Sjögren syndrome ... • Systemic lupus ... erythematosus ... vasculitides
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... : - Arthritis ... and Lupus Mimickers ... #Lupus #Erythematosus ... #signs #symptoms