11 results
hematology causes workup abnormal anemias apml chemistry classification differentiation elevated extravascular hemolysis hodgkins interpretation intravascular liver liverfunctiontests lymphoma mcv monoclonal
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm ... • Extrinsic RBC ... • Intrinsic RBC ... #Anemias #Differential ... #Diagnosis #Algorithm
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Diagnosis Algorithm ... Decreased WBCs ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... Diagnosis #Algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Ducts - PBC ... Burak @kwburak #LFTs ... #Algorithm #diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Diagnosis Framework ... Spherocytosis, G6PD, PK, HbC ... Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... elliptocytosis - RBC ... anemia • ... #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Diagnosis Algorithm ... hypertension • Unusual RBC ... #Anemia #Differential ... #Diagnosis #Algorithm
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Diagnosis Algorithm ... Initial Workup: CBC ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... #Diagnosis #Algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... #differential # ... Hepatology #transaminitis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... QD until normal WBC ... #management #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
+Organomegaly+↑RBC ... • Coombs (-) hemolytic ... anemia due to cold ... #Monoclonal #Differential ... #Diagnosis #Oncology
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