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RBC Casts on Urine Microscopy

Dr. Telma Lemos @TELMALEMOS10

#RBC #Casts #Urine #Microscopy #clinical #nephrology
RBC Casts on Urine ... Microscopy Dr. ... TELMALEMOS10 #RBC ... #Casts #Urine #Microscopy ... #clinical #nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... glomerular hematuria (RBC ... or dysmorphic RBCs ... Comparison #Algorithm #Nephrology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Red Blood Cell (RBC ... cell, Other RBC ... Howell-Jolly bodies #RBC ... Morphologies #Key #Atlas #Microscopy ... #Pathology #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
(Pancytopenia, WBC ... Lymphocytic Leukemia (CBC ... Algorithm #Causes #Hematology ... #Oncology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... urine sediment - WBC ... /RBC casts ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... Cellular Casts: • RBC ... glomerulonephritis • WBC ... #Casts #Urine #Microscopy ... #nephrology #interpretation
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Bite Cell RBC: G6PD ... differential #diagnosis #hematology ... #microscopy #atlas
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Drug-associated, PCH, Evans Syndrome ... 3) Internal (RBC ... Smear ↑ abnormal RBCs ... Differential #Diagnosis #hematology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria: 3 or more RBC ... pain hematuria syndrome ... hematuria: - RBC ... - Dysmorphic RBC ... causes #urology #nephrology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... Leukostasis: • WBC ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome