16 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... and renal manifestations ... Renal Syndromes ... polyangiitis, Microscopic ... #Renal #Syndrome
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... Diagnostic of GN or vasculitis ... • Nutcracker syndrome ... causes #urology #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... vasculitis (AAV ... Renal Syndromes ... and renal involvement ... #Renal #Syndromes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and renal abnormalities ... ): • Microscopic ... Lab Tests: • CBC ... Dx: GPA, EGPA, microscopic ... (Renal involvement
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... biliary cirrhosis (PBC ... - Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Glomerulonephritis / Vasculits ... Abdominal compartment syndrome ... syndrome: troponin ... Differential #Diagnosis #nephrology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- BMP, cap, CBC ... - Urinalysis/microscopy ... pre-renal) - ... Glomerulonephritis or vasculitis ... AcuteKidneyInjury #AKI #Nephrology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... Leukostasis: • WBC ... Hoarseness • Chest and ... Hyperuricemia • Acute renal
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... cases • Sjögren syndrome ... Vasculitis: • ... Microscopic polyangiitis ... vasculitis - MPO
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... diagnosis #management #hematology ... #oncology