66 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
biliary cirrhosis (PBC ... lupus erythematosus ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... central nervous system ... and treatment can ... • Systemic lupus
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... #management #treatment
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... SLE), Sjogren's Syndrome ... : Lupus (SLE), Systemic ... Arthritis, Sjögren Syndrome ... #diagnosis #differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #signs #symptoms ... #differential #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... skin thickening Signs ... and Symptoms: ... #diagnosis #signs ... #symptoms #testing