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erythematosus management differential classification signs oncology syndrome criteria vasculitis workup activation agglutinin antibodies antinuclear arthritis autoantibodies behcet cerebritis chronic cll
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Clinical and Immunologic ... anemia #Diagnosis ... #Rheumatology # ... SLE #Lupus #Erythematosus
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... : • Systemic lupus ... hemoglobinuria • Antibody-mediated ... hemolysis Nutritional ... #Hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... ) Blood (75%): Anemia ... #SLE #systemic ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... and Lupus Mimickers ... #Systemic #Lupus ... #differential #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... ) Clinical Manifestations ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology #
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... pericarditis • Hematologic ... #Systemic #Lupus ... Erythematosus #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibody refers ... context of other symptoms ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... and CNS • Headache ... : • Symptoms limited ... #Systemic #Lupus ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... Diagnosis: • hemolytic ... Blood smear - RBC ... #hemolytic #anemia ... #hematology #diagnosis
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