351 results
diagnosis management algorithm causes hematology syndrome hepatology rheumatology workup neurology nephrology cardiology pulmonary anemia gastroenterology oncology table clinical dermatology criticalcare
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... if high risk if WBC ... initiation • Differential ... QD until normal WBC
Algorithm and Differential Diagnosis of Macroscopic Hematuria Important Historical Elements: - Painless: suggests malignancy - Painful: suggests calculi/infection - Urinalysis:
Algorithm and Differential ... dysmorphic RBC’s, RBC ... /WBC casts, proteinuria ... #Macroscopic #Differential
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Lymphadenopathy - Differential ... (Pancytopenia, WBC ... differential includes ... Lymphocytic Leukemia (CBC ... Lymphadenopathy #LAD #Differential
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
Pathophysiology ... - Defects in RBC ... - Defects in RBC ... environment #Pathophysiology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... Even with normal WBC ... 21% had normal WBC ... #Bandemia #differential ... #pathophysiology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... platelets, persistent WBC ... #Leukocytosis #Differential ... Algorithm #hematology #WBC
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... ischemia-induced RBC ... hemolysis) • RBC ... #Hyperkalemia #Differential ... potassium #high #pathophysiology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Algorithm Decreased WBCs ... Normal/lncreased WBCs ... Spherocytes, RBC ... Normocytic #Anemia #Differential
Peritonitis - Spontaneous vs Secondary vs Peritoneal Dialysis Associated Peritonitis Spontaneous Bacterial Peritonitis • Cirrhosis (high SAAG)
PMN > 250 • Treatment ... cloudy effluent) 2) WBC ... > 100 WBC, >50% ... Positive Culture • Treatment ... Peritoneal #diagnosis #differential
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... • Lab values: WBC ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology
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