14 results
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... bleeding (proteinuria ... , RBC casts, dysmorphic ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... - Differential Diagnosis ... • Drugs Glomerular ... /RBC casts ... #Nephrology #Differential
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... Proteinuria often ... diabetes)) #Glomerular ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular ... hematuria (RBC ... Comparison #Algorithm #Nephrology ... #Diagnosis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... castsDiagnostic ... Brown urine - Proteinuria ... #causes #urology ... #nephrology #renal
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
- Differential Diagnosis ... Atherosclerosis Glomerular ... (Proteinuria) ... Sterile pyuria, WBC ... KidneyDisease #Nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
antigen, hepatitis C antibody ... infections are common causes ... #testing #workup ... #diagnosis #glomerulonephritis ... nephrotic #nephritic #nephrology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... body-like: - Neurologic ... #Antibody #Testing ... #differential #diagnosis ... #rheumatology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... antigen, hepatitis C antibody ... infections are common causes ... #workup #diagnosis ... initial #testing #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
, RBC casts, +/- ... proteinuria) ... formation along glomerular ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal