18 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
to Anemia - Differential ... • Anemia of Chronic ... #Classification ... #Approach #Differential ... #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... #Morphology #differential ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... usually IgG) (e.g. lupus ... Extravascular #Causes #differential ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... for workup, including ... , deficiency anemia ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
of Chronic Disease ... • Bleeding • Hemolysis ... of Chronic Disease ... #MCV #Classification ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Diagnosis Framework ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... #Anemia #Differential ... #workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
kidney disease, ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... anemia Indirect ... from ischemia WBC ... count and differential ... #Workup #Hematology