27 results
oncology anemia causes hemolysis hemolytic intravascular chronic classification eosinophils extravascular hemeonc hepatitis hypereosinophilia leukemia liver lymphocytic thrombocytopenia workup abnormal agglutinin
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... and Treatment Algorithm ... #HES #Hematology ... eosinophils #diagnosis ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
(HES) - Diagnosis ... than 1500 and clinical ... #diagnosis #hematology ... #differential # ... management #eosinophils
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... • Sickle cell ... elliptocytosis - RBC ... #Diagnosis #Algorithm ... #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... - MAHA: TTP, HUS ... Drug-associated, PCH, Evans Syndrome ... #Diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Agent Orange or Hep ... C Clinical Presentation ... Diagnosis: • ... microglobulin Treatment ... workup #oncology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... (HUS) • Other ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... • Lab values: WBC ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... • Induce blast cell ... initiation • Differential ... #management #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... Consider sickle cell ... DIC, TTP, HELLP, HUS ... #Diagnosis #Algorithm ... #workup #hematology
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