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management syndrome algorithm chronic cll differential lymphocytic mds myelodysplastic workup anemia antibody antinuclear aplastic behcet cancer causes cell cerebritis ckd
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... APML, CLL Acute ... smear: Blasts APML ... #Hematology #Oncology ... #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... if high risk if WBC ... Renal Failure Treatment ... QD until normal WBC ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... transformation to acute leukemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis on CBC ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... lymphadenopathy and ... #oncology #hematology ... #hemeonc #diagnosis
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Polycythemia Vera (PV) - Diagnosis ... Summary Diagnostic ... incidentally via CBC ... transformation into AML ... #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
conditions - Sp-100, PML ... body-like: - Neurologic ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... • ↓ WBC • ↓ ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
, breast CA - Hematologic ... cutis Diagnosis ... - CBC may also ... Treatment: - Systemic ... #dermatology #oncology
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