67 results
diagnosis hematology differential management algorithm anemia syndrome causes systemic hemolytic sle erythematosus summary arthritis classification neurology pancytopenia syndromes testing antibodies
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Systemic Lupus ... (Pancytopenia, WBC ... Lymphocytic Leukemia (CBC ... Algorithm #Causes #Hematology ... #Oncology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... , Drug-induced Lupus ... Disorders, Infection, Autoimmune ... Thyroid, Autoimmune ... ANA #patterns #rheumatology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... spherocytosis, Autoimmune ... Target Cell RBC ... Agglutinate: Cold autoimmune ... differential #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
hypertension • Unusual RBC ... acanthocytes - Consider RBC ... elliptocytosis, autoimmune ... Diagnosis #Algorithm #workup ... #hematology #testing
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Immune-mediated: - Autoimmune ... usually IgG) (e.g. lupus ... idiopathic) - Autoimmune ... • Intrinsic RBC ... differential #diagnosis #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and their Disease ... common in SLE, autoimmune ... microsomal) - Autoimmune ... biliary cirrhosis (PBC ... diagnosis #table #rheumatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... ↑ LDH • Anti-RBC ... Warm #Antibody #Autoimmune ... diagnosis #management #treatment ... #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Vmphocytosis on routine CBC ... transformation) Treatment ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Autoimmune Mediated ... Autoimmune condition ... Metastatic Disease ... #Pancytopenia #Workup
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