5859 results
Nitrofurantoin Toxicology
Serious Adverse Effects:
Hemolysis in patients with G6PD-deficiency
Peripheral neuropathy
Hepatitis
Pulmonary toxicity
Nephritis

By Dr. Kathryn Watson @Kat_Watson

#Nitrofurantoin #Macrobid #Toxicity
Hepatitis Pulmonary toxicity ... Kathryn Watson @ ... Nitrofurantoin #Macrobid #Toxicity ... #Pharmacology #Diagnosis
Carbamazepine Toxicity

Carbamazepine (CBZ) is an antiepileptic drug commonly prescribed for seizure disorders, trigeminal neuralgia, neuropathic pain,
Carbamazepine Toxicity ... Kathryn Watson @ ... Carbamazepine #Toxicity ... #Toxicology #Diagnosis
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
Symptoms of GHB toxicity ... Kathryn Watson @ ... GHB #Toxicology #Toxicity ... #Diagnosis #Management
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... absent in severe toxicity ... Kathryn Watson @ ... Iron #Poisoning #Toxicity ... #Toxicology #Diagnosis
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Toxicology Acute toxicity ... Chronic toxicity ... than with acute toxicity ... Kathryn Watson @ ... #Pharmacology #Diagnosis
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Syndrome (PRIS) Diagnosis ... Kathryn Watson @ ... Syndrome #PRIS #Diagnosis ... #Pharmacology #Toxicity
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Kathryn Watson @ ... #Colchicine #Toxicity ... #Pharmacology #Diagnosis
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
anaerobic metabolism Diagnosis ... Kathryn Watson @ ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
alcohol consumption Diagnostic ... immediately Kat Watson ... Euglycemic #DKA #EDKA #Toxicity
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Kathryn Watson @ ... Prolonged #QTc #Toxicity ... #Pharmacology #Diagnosis