10 results
Signs and Symptoms of Toxidromes

Sympathomimetic / GABAergic withdrawal 
Cholinergic 
Anticholinergic 
Opioid withdrawal 
Neuroleptic malignant syndrome 
Serotonin
Signs and Symptoms ... Anticholinergic Opioid ... #Toxidromes #Comparison ... Anticholinergics #Opioids ... Sympathomimetics #Diagnosis #Toxicology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
syndrome (set of symptoms ... phyostigmine) - Opioid ... #Diagnosis #Toxicology ... #Toxidromes #Comparison ... Anticholinergics #Opioids
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
withdrawal symptoms ... prevents withdrawal symptoms ... margin of safety in pharmacology ... Pharmacokinetics #Comparison ... #Table #Pharmacology
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... presentation - Symptoms ... Kathryn Watson @ ... Hydroxybutyrate #GHB #Toxicology ... Diagnosis #Management #Pharmacology
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... /IO/SQ for non-opioid ... Kat Watson @Kat_Watson ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
Phases of Colchicine ... cardiac arrest Neurologic ... Kathryn Watson @ ... #Toxicity #Toxicology ... #Phases #Pharmacology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kathryn Watson @ ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis ... #management #nephrology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... effect on negative symptoms ... Kathryn Watson @ ... #Clozapine #Toxicology ... Toxicity #Diagnosis #Pharmacology
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Prochlorperazine • Opioids ... Kathryn Watson @ ... QTc #Toxicity #Toxicology ... #Pharmacology #
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
Tramadol - Toxicology ... mix of SNRI and opioid ... Kathryn Watson @ ... #Tramadol #Toxicology ... Toxicity #Diagnosis #Pharmacology