26 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Abnormal Coagulation Tests ... PT - Prolonged aPTT ... PT - Prolonged aPTT ... #Laboratory #Hematology ... #Diagnosis #Workup
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... • Clotting tests ... PT and/or aPTT) ... Study #diagnosis #hematology ... pathophysiology #hematology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Vascular imaging → Test ... - No other workup ... screening, CBC, aPTT ... Hypercoagulable #Workup ... #hematology #diagnosis
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
/uL Initial Workup ... iron studies, PT/aPTT ... Diagnosis #Algorithm #hematology ... #workup
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Direct antiglobulin test ... , PT/aPTT MAHA ... hemosiderin • PT/aPTT ... Management #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... cases: INR/PT, aPTT ... K), H. pylori test ... thyroid function test ... #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... • Underfilled test ... thematttsai #PT #PTT ... Thromboplastin #laboratory #hematology
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm

Radioactive iodine scan – get if concern for nodular
Check pregnancy test ... affects diagnostic workup ... Diagnosis #Algorithm #Workup ... #Endocrinology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Differential #Causes #Workup ... #Hematology #Diagnosis ... GrepMed Recommended Text
Adrenal Incidentalomas: Hormone Evaluation
 • Zona Glomerulosa: Primary Hyperaldosteronism?
    - Aldosterone and renin
dexamethasone test ... Evaluation #Diagnosis #workup ... #endocrinology