11 results
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
in (Antiphospholipid ... Syndrome) APS ... #Syndrome #APS ... EULAR2019 #guidelines #rheumatology ... #hematology #treatment
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... ): • Lupus anticoagulant ... or small-vessel thrombosis ... to be present Treatment ... #Syndrome #APS
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

• No previous history of
low-molecular-weight heparin in lupus ... and Antiphospholipid ... Syndrome (APS) ... BUT high-risk aPL ... #Syndrome #APS
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS
Previous Thrombosis?
Previous Pregnancy Complications?

Dr. Laurent ARNAUD @Lupusreference

#obstetrics
Syndrome) APS ... Previous Thrombosis ... #Syndrome #APS ... EULAR2019 #guidelines #rheumatology ... #obgyn #treatment
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

 -
Differential Diagnosis: Rheumatologic ... Hypercoagulable state (eg APLA ... Vascular: embolic/ thrombotic ... Hypothyroidism - Carpal ... tunnel syndrome
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... , others (RNP, aPL ... antibodies) • Antiphospholipid ... Antibody Syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... vasculopathy, thrombosis ... Puncture, EEG Treatment ... (for secondary APS ... CNS #neurology #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... Malignancy - Antiphospholipid ... antibodies (APLS ... pathophysiology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Antiribosomal P, APLA ... disorders • CAD APLA ... valve vegetations APLA ... Erythematosus #Diagnosis #Rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... or small-vessel thrombosis ... excluded Testing: • Lupus ... #Antiphospholipid