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diagnosis differential management symptoms hematology dermatology disease algorithm arthritis associations autoantibodies classification cppd diseases erythematosus gout joint lupus pain pathophysiology
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Involvement, Spares DIP, Carpal ... Tunnel, Sicca Syndrome ... Disease, Rheumatoid Vasculitis ... #diagnosis #rheumatology ... #signs #symptoms
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Rheumatoid factor - RA ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... diagnosis #table #rheumatology ... #antibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... LAC) • Sjogren Syndrome ... ribonucleoprotein) • RA ... Polymerase Ill • ANCA Vasculitis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
small joints (wrists ... characteristic antibodies ... boggy" joints, esp carpal ... fingers, radial wrist ... Extra-articular signs
Raynaud Phenomenon Differential Diagnosis: Rheumatologic - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD Heme -
Differential Diagnosis: Rheumatologic ... systemic sclerosis, RA ... , SLE, Sjogren syndrome ... Hypothyroidism - Carpal ... tunnel syndrome
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... Secondary: CTD: SLE, RA ... related vasculitis ... Disease • Cogan syndrome ... #dermatology #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Alloimmune • anti-HLA antibodies ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... Algorithm #Causes #Hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... cases • Sjögren syndrome ... ANCA-Associated Vasculitis ... Renal-limited vasculitis ... #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... arteritis, Cogan's Syndrome ... ANCA associated vasculitis ... Rheumatoid Arthritis (RA ... Differential #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology
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