14 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #algorithm
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... 10x ULN), ↑Tbili/Dbili ... infiltration) Differential ... Diagnosis: Viral ... #management #pathophysiology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... #diagnosis #algorithm
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... 2) Presence of symptoms ... history (cardiac, liver ... #EM #IM #Nephro ... #Algorithm #Ddxof
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
(IBS) - Pathophysiology ... , Diagnosis and ... Management Algorithm ... factors affecting symptom ... #Diagnosis #Management
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... and Management ... - Activation: Liver ... #differential # ... algorithm
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Insufficiency, Liver ... Abdominal compartment syndrome ... #algorithm #treatment ... #management
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... suspicious clinical symptoms ... presence of metabolic syndrome ... LFTs #Abnormal #Algorithm ... #Enzymes #Differential
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... survival is 93-95% Pathophysiology ... heart (2-5%), liver ... #Management #Signs
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... #management #hematology